Perfect detection is a fantasy. It's a resource sink chasing an impossible goal.
Focus on raising the cost for the attacker instead.
* Baseline normal agent telemetry: process trees, network destinations, volume.
* Hunt for deviations: new outbound protocols, beaconing to unknown ASNs, data volumes mismatching task.
* Example: an agent doing DNS lookups for internal hosts suddenly starts HTTPS POSTs to a new IP in a bulletproof hosting range. That's your signal.
The goal isn't to catch everything. It's to make exfiltration so noisy and expensive that the operation fails or you catch it during setup. If your detection needs to be perfect, your response and containment are too slow.
- Helen